The science
Your biology,
rendered as a formula.
~710,000 genotypes per sample, filtered to the 200+ markers with the strongest published links to nutrient metabolism. Evaluated against a proprietary rules engine. Blended into one bottle.
Primer
What is a SNP?
Single nucleotide polymorphisms, SNPs, pronounced “snips”, are single-letter variations in your DNA. They’re the reason two people can take the same supplement and experience entirely different results.
A SNP in your MTHFR gene can drop folate activation by up to 70%. A SNP in VDR means your vitamin D receptor responds less efficiently. A SNP in PEMT weakens your body’s ability to synthesize choline from scratch.
Millions of SNPs exist. We’ve curated the 200+ with the clearest evidence linking genotype to nutrient need, and built a formula engine around them.
How the field got here
None of this is new. It’s just newly affordable.
Trait didn’t invent nutrigenomics. We stand on seventy years of published science. Every milestone below is a real, documented event, click any source and verify it yourself.
1953
The double helix
Watson and Crick describe the structure of DNA in Nature — the physical basis for how genetic information is stored and copied.
Nature 171:737 (1953) ↗1990
The Human Genome Project begins
An international public effort launches to read all ~3 billion letters of human DNA — the reference every modern genetic test is compared against.
genome.gov — HGP ↗1995
MTHFR is linked to folate metabolism
Frosst and colleagues identify the common C677T variant in MTHFR that reduces folate-processing enzyme activity — one of the most-studied nutrient-related variants, and a tier-1 marker in our panel.
Nat Genet 10:111, PMID 7647779 ↗2003
The genome is finished
The Human Genome Project completes a reference sequence of human DNA, on the 50th anniversary of the double helix. Reading a person's genome shifts from science fiction to routine.
genome.gov — 2003 completion ↗2005
A map of human variation (HapMap)
The International HapMap Project catalogs the common SNPs that differ between people — the exact variation that makes one person's nutrient needs differ from another's.
Nature 437:1299 (2005) ↗2008
GINA becomes law
The Genetic Information Nondiscrimination Act makes it illegal for health insurers and employers to use your genetic information against you — the legal floor that makes consumer genomics safe to participate in.
Public Law 110-233 ↗2014
Proof that people act on their genes
A 1,000-person randomized trial shows that giving people DNA-based nutrition guidance actually changes what they do — evidence that personalization is not just interesting, but actionable.
PLoS One 9:e112665, El-Sohemy ↗2018
Personalized nutrition enters the mainstream
A landmark BMJ review concludes that nutrition guided by individual biology — including genotype — outperforms one-size-fits-all dietary advice.
BMJ 361:k2173 (2018) ↗
In the field’s own words
“We have caught the first glimpse of our own instruction book, previously known only to God.”
Dr. Francis Collins — geneticist who led the Human Genome Project and later directed the U.S. National Institutes of Health, announcing the first draft of the human genome, June 2000.
Two decades later, that instruction book is readable for the price of a nice dinner. The science was always there. What changed is that a person can now afford to have their own copy read, and to do something useful with it.
Quotation attributed to Dr. Collins is a matter of public record. Dr. Collins is not affiliated with and does not endorse Trait.
The pipeline
From genotype to nutrient action.
Eight of the ten biological categories we evaluate, and the nutrient actions they trigger. The weights reflect approximate rule density, methylation alone involves six genes and dozens of interacting variants.
The panel composition
10 categories.
One coherent formula.
Each marker belongs to one of ten biological systems. The rules engine weights them against each other, for example, a methylation variant that would normally push more methylfolate is softened if you also carry a COMT slow variant.
The output is a formula that’s internally consistent, not a pile of independent recommendations.
Hover a sector to explore, figures illustrative of the Trait panel composition.
End to end
From sample to bottle.
DNA Sample
~710,000 genotypes
Curated Panel
200+ markers
Rules Engine
Genotype → nutrients
Conflict Resolution
Interactions checked
Your Formula
Custom-blended
DNA Sample
~710,000 genotypes
Curated Panel
200+ markers
Rules Engine
Genotype → nutrients
Conflict Resolution
Interactions checked
Your Formula
Custom-blended
Worked example
Four real variants. Four real adjustments.
Scroll through four SNPs from the panel. Each card shows the variant, the biological readout, and the exact nutrient action — while the formula panel on the right assembles in real time.
Detected variant: C677T (CT or TT)
Readout — Reduced folate cycling
Action — Switch folic acid → active methylfolate
Detected variant: FF (FokI variant)
Readout — Lower vitamin D receptor response
Action — Titrate cholecalciferol above base
Detected variant: AA
Readout — Weaker endogenous choline synthesis
Action — Add choline (non-base ingredient)
Detected variant: CC
Readout — Mitochondrial oxidative vulnerability
Action — Add mitochondrial antioxidant stack
Your formula, building now
One bottle,
shaped by your DNA.
5-MTHF (active folate)
via MTHFR C677T
Vitamin D3
via VDR FF
Phosphatidylcholine
via PEMT AA
CoQ10 + NAC
via SOD2 CC
Illustrative example. Your real formula is generated from your complete ~200-marker panel, often 12-20 targeted additions layered on a foundational base of essentials.
Straight answers
What this is, and what it isn’t.
What it is
- A way to match well-evidenced nutrients to the specific variants in your DNA, instead of guessing.
- Built on published, peer-reviewed research — every marker traces back to a citation.
- Read once. Your DNA doesn’t change, so the analysis stays valid for life.
- A wellness and nutrition tool, designed to support how your body already works.
What it isn’t
- Not a diagnosis. We don’t test for diseases, and we don’t predict them.
- Not a clinical genetic test, carrier screen, or ancestry report.
- Not a replacement for your doctor. Talk to a clinician before changing anything, especially on medication.
- Not a promise of a specific outcome. Biology varies, and we won’t pretend otherwise.
Verified
Lab-grade. Standards-bound.
CLIA
Certified Lab
#26D2106631
CAP
Accredited
Pathology standards
NSF
cGMP Certified
Manufacturing
Genotyping by Dynamic DNA Labs (CLIA #26D2106631, CAP-accredited, Springfield, MO). Manufacturing by Personalized Nutrients at an NSF cGMP-certified facility in Sisters, Oregon.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.